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Original Article
Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
Clin Exp Pediatr. 1995;38(8):1077-1086.   Published online August 15, 1995
Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...
Erratum
Three Cases of Necrotizing Lymphadenitis in Childhood
Seong Hoon Hah, Dong Woon Shin, Kyung Hee Lee, Tae Sun Ha, Beom Soo Park, Heon Seok Han, Sang-Hoon Cha, Geon Kook Lee
Accepted January 1, 1970  
Necrotizing lymphadenitis(named as "Kikuchi disease"), initially described by a Japanese pathologist as "a histiocytic necrotizing lymphadenitis with paracortical necrosis, plasmacytoid monocytes infiltration and prominent phagocytic appearance" has been found worldwide. Be-cause of its self-limited course, it has been well known that what should be considered as more important issues are its deatiled pathologic criteria for confirmation and thorough concern about...
Case Report
One Case of Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome due to Mycoplasma pneumoniae In fection
Soo Kyung Lee, Joon Soo Lee, Soo Young Lee, Byung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1993;36(10):1441-1446.   Published online October 15, 1993
Bronchiolitis obliterans is an infrequent disorder characterized by partial or complete obstruction of bronchi and bronchioles by fibrous tissue following an insult to the lower respiratory tract. In the pediatric population, Bronchiolitis obliterans has most frequently been preceded by respiratory tract infection by adenovirus, influenza, measles. But it may occur in young adults after mycoplasma infection. We experienced the case...
Original Article
A Clinical Study on Wheezing of Mycoplasma Pneumoniae Pneumonia in Children
Jeong Eun Kwon, Jun Ho Yoon, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1993;36(10):1366-1374.   Published online October 15, 1993
The relationship between respiratory infections and exacerbations of wheezing in patients with wheezy bronchitis or asthma has been described. Most respiratory infections were viral or Mycoplasma pneumoniae. This study was performed to evaluate the effect of Mycoplasma pneumoniae infection on bronchial reactivity and atopic background. 106 patients with Mycoplasma pneumoniae pneumonia who were admitted to the department of pediatrics, Fatima Hospital,...
Clinical Consideration between the Type of pneumonia and cold Agglutinin Titer, and Mycoplasma Antibody Titer caused by Mycoplasma pneumonia in Children
Byung Yeon Kim, Hyang Suk Lee, Ill Kyung Kim, Chang Hee Choi, Jyung Ho You
Clin Exp Pediatr. 1993;36(7):959-967.   Published online July 15, 1993
The authors analysed 261 cases of mycoplasmal pneumonia in chidren who were admitted to the pediatric department of Seoul Adventist Hospital between July 1986 and June 1991. The result obtained were as follows; 1) Yearly distribution of the cases showed high in 1987 and 1991, but no significant difference was noted in seasonally or monthly distribution. 2) The peak incidence of age was...
A Clinical Study of Mycoplasma Pneumonia in Children During Recent 5 Years
In Seung Park, Ha Baik Lee
Clin Exp Pediatr. 1992;35(8):1082-1088.   Published online August 15, 1992
Mycoplasma pneumoniae infections are among the most frequent respiratory diseases of school-aged children, adolescents and young adults. However in preschool children a persistent nonproductive cough, fever and interstitial or lobular infiltrates on the chest radiograph can recently be recognized as presenting features of M. pneumoniae. We studied to find out the recent trends in epidermiologic and clinical variabilities of M. pneumoniae...
Clinical Study of Mycoplasmal Pneumonia Syndrome in Children
Hyeon-Hi Kim, Hung-Ki Min, Seung-Hoon Han, Jin-Han Kang, Joon-Sung Lee, Sung-Hoon Cho
Clin Exp Pediatr. 1992;35(4):451-458.   Published online April 15, 1992
Between September 1, 1989 and August 31, 1990, we studied 142 cases of mycoplasmal p neumonia syndrome in children who were admitted to the pediatric department of Catholic University Medical College. The results were as follows; 1) The highest incidence was in the age of 6 years in 27 cases and the male to female ratio...
The diagnosis of mycoplasma pneumoniae pneumonia by high density composite particles agglutinin test.
Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Kyu Chul Choeh
Clin Exp Pediatr. 1991;34(8):1102-1109.   Published online August 31, 1991
In a prospective investigation of 21 chi Idem 3 years of age or more with Mycoplasma pneumoniae pneumonia, we analyzed the diagnostic efficacy of High Density Composite Particles Agglutinin(HDDA) test comparing with cold agglutinin tests and clinical findings. The results obtained were as followed. 1) Among 24 total cases, the number of cases showing positive reaction to HDPA and to cold agglutination test were 17 and...
A clinical study of pneumonia presented with positive cold agglutin- in test.
Il Jung Joo, Jin Seop Juong, Sang Woo Kim
Clin Exp Pediatr. 1991;34(8):1093-1101.   Published online August 31, 1991
A clinical study was performed on 65 patients with Mycoplasma pneumoniae pneumonia who were admitted to the Department of Pediatrics of Seoul Paik hospital from September 1,1989 to August 31, 1990. The results were as follows; 1) Seasonal distribution showed a high frequency in summer (33 cases; 50.8%). 2) The peak incidence was 5 to 9 years of age (32cases;49.2%). 3) Male to female ratio was 1:1.17(30:35). 4) On the chest...
A case of pancytopenia associated with mycoplasmal pneumonia.
Young Mee Yoo, Beom Soo Park, In Sang Jeon, Hee Young Shin, Hyo Seop Ahn, Se Jung Sohn
Clin Exp Pediatr. 1991;34(6):826-831.   Published online June 30, 1991
Mycoplasma pneumoniae infection is manifestated as pneumonia and extra-pulmonary symptoms such as hematologic, neurologic, gastrointestinal, musculoskeletal, dermatologic and cardiac manifes- tations. Among the hematologic changes, hemolytic anemia is most frequently seen. Throm- bocytopenic purpura, lymphocytosis or rarely lymphopenia, elevated erythrocyte sedimentation rate, positive direct Coombs test, reticulocytosis and DIC are known hematologic features. This 12 years old female patient was presented with pneumonia and pancytopenia....
Therapeutic effects of plasmapheresis in Guillian-Barre syndrome.
Sung Jin Chang, Sun Hee Jung, Eun Sook Suh, Chin Moo Kang
Clin Exp Pediatr. 1991;34(1):66-73.   Published online January 31, 1991
Although the exact mechanism of the immunologic injury is unknown, the pathogenesis of the Guillain-Barr受 syndrome is explained as an autoimmune attack directed against to peripheral nervous myelin. So plasmapheresis is tried for treatment of Guillain-Barr즌 syndrome. Authors analysed 12 cases af Guillain-Barr受 syndrome who were treated with plasmapheresis and compared the results with that of the 13 cases, treated with conventional therapy. Duration between...
Clinical Study of Mycoplasma Pneumoniae Infection in Children.
Jong Woon Choi, Hoan Jong Lee, Byung Kiu Park, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(3):315-323.   Published online March 31, 1990
A retrospective analysis of clinical findings in 43 patients with M. pneumoniae infection who visited Department of Pediatrics of Seoul National University Hospital from January, 1987 till December, 1987 was performed. 1) The peak incidence of age was 5 to 9 years of age (20 cases; 46.5%), and male-to-female ratio was 1.05:1. 2) Monthly distribution showed a high frequency in April (10 cases; 23.3%) and seasonal distribution showed...
A case of Guillain-Barré syndrome in a child treated with plasmapheresis.
Hae Won Lee, Hoo Jae Han, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1989;32(11):1592-1597.   Published online November 30, 1989
We experienced a case of Guillain -Barré syndrome in a 12-year-old female patient who had progressive motor weakness and showed rapid recovery with plasmapheresis and supportive therapy in acute stage. A brief review of the related literature was added.
Role of aldosterone on the minimal change nephrotic syndrome in children.
Soon Wha Kim, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1989;32(11):1526-1532.   Published online November 30, 1989
We studied 11 cases of minimal change nephrotic syndrome randomly selected among 16 cases of minimal change nephrotic syndrome who were proved by kidney biopsy at department of pediatrics, National Medical Center during the period of January 1985 through December 1987. These patients were studied serially at 3 different stages in their clinical course. These were stages of edema formation, diuresis and remission, respectively. The...
Plasma Amino Acid Patterns in Reye's Syndrome.
Han Wook Yoo, Hee Shang Youn
Clin Exp Pediatr. 1989;32(10):1377-1383.   Published online October 31, 1989
The metabolic disturbances of Reye’s syndrome are many and involve carbohydrates, amino acids, free fatty acids, proteins, ammonia and acid-base balance. It has been suggested that the derangement of mitochondrial integrity by an agent or agents unknown leads to a loss of enzyme activity in many metabolic pathways in which t노e mitochondria are involoved. Of primary interests in this study is the abnormalities regarding...
A Study on the Change of Plasma Renin Activity(PRA) and Aldosterone Concentration(PAC) before and after Heart Operation in Children with Congenital Heart Disease.
Jae Hong You, Jae Ho Lee
Clin Exp Pediatr. 1989;32(9):1232-1239.   Published online September 30, 1989
Thes is a study on changes of plasma renin activity (PRA) and aldosterone concentration (PAC) which was obtained before and after heart operation in 26 normotensive children with congenital heart diseases without renal disease admitted in Chungnam National University Hospital for cardiac catheterization with angiogram and heart operation from Apr. 1988 to Aug. 1988 to confirm any differences of PRA and PAC between groups...
Unusual Forms of Pulmonary and Extrapulmonary Manifestations of Mycoplasmal Pneumonia.
Young Soo Lee, Chang Ho Hong, Chul Lee, Sung Gyu Lee
Clin Exp Pediatr. 1989;32(8):1064-1073.   Published online August 31, 1989
A clinical study was performed on 145 patients admitted to the Departement of Pediatrics, Yong Dong Severance Hospital between July, 1984 and June, 1987 with the diagnosis of Mycoplasmal pneumonia. This diagnosis was done when chest X-ray or auscultation of the chest showed signs of pneumonia. Patients with cold agglutinin titrations of 1:64 or titrations with four fold increase during follow up had Indirect...
Clinical Study of Interrelationship Between Cold Agglutinin Titers and Indirect Hemagglutination Titers in Children with Mycoplasma Pneumoniae Pneumonia During Recent 3 Years.
Jong Chan Shin, Jae Youn Kim, Myung Ik Lee, Soon Wha Kim, Keun Chan Sohn, Kyeung Eun Jung
Clin Exp Pediatr. 1989;32(7):915-925.   Published online July 31, 1989
A clinical study was made on 103 cases of Mycoplasma pneumoniae pneumonia patients during the period of 3 years from July ’84 to June '87. Indirect hemagglutination test (IHA) and/or cold agglutinin test (CAT) were measured and follow-up studies were done until the 50th day of the illness. Each titer was compared for analysis of interrelationship between them. And we obtained following results: 1) The highest...
A Case of Mycoplasmal Meningitis Associated with Mycoplasma Pneumoniae Pneumonia.
Sang Young Jeong, Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(4):556-560.   Published online April 30, 1989
Mycoplasmas have been recognized as pathogens of respiratory tract in children and adolescence, but clinically apparent pneumonia develops in only 3 to 10% of infected persons. Central nervous system complication, such as aseptic meningitis, meningoencephalitis. transverse myelitis, hemiplegia, cerebellar ataxia and psychosis, associated with Mycoplasma pneumoniae infection were developed in .0.1 % of all Mycoplasmal infection. We experienced a case of Mycoplasma pneumoniae pneumonia and...
Clinical Consideration on Pneumonia caused by Mycoplasma Pneumoniae in Children.
Il Kyung Kim, Hyung Jin Kwon, Ho Seong, Chang Hee Choi
Clin Exp Pediatr. 1989;32(1):1-10.   Published online January 31, 1989
A retrospective analysis of clinical findings in 63 patients above 2 years of age who were admitted to our hospital due to pneumonia caused by Mycoplasma pneumoniae from July, 1986 to June, 1987 was performed. The results obtained were as follows: 1) The number of patients showing positive reaction to cold agglutinin test (above 1:64) were 59 (55. 7%) among 106 total pneumonia cases. 2) The...
A Clinical Study of Mycoplasma Pneumoniae Pneumonia.
Jeong Wi Yook, Sun Ock Kim, Min Shik Kim, Hey Sun Lee, Young Min Ahn, Dae Young Kim
Clin Exp Pediatr. 1988;31(12):1603-1611.   Published online December 31, 1988
A clinical study was made on 114 cases of Mycoplasma pneumoniae pneumoniae pneumonia during the period of 3-6/12 years from April, 84 to September, 87. The results were as follows; 1) Among the 920 cases of lower respiratory tract infections, the incidence of Mycoplasma infection was 25.4%(234/920). 2) The mean age was 6.2 ±2.9 years and the male to female ratio was 1:1.1. 3) There was no significant seasonal...
Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children with Cyanotic Congenital Heart Disease.
Sang Kyu Park, Hae Il Cheong, Chung Il Noh, Yong Soo Yun, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1988;31(8):1021-1027.   Published online August 31, 1988
PRA’s in peripheral vein, both renal veins, and inferior vena cava (IVC) were measured in 25 normotensive children without renal disease undergoing cardiac catheterization for their underlying cyanotic congenital heart disease. And we presented the results as reference values/ranges of PRA in children. 1) There was no significant difference in PRA between both side renal veins at any absolute PRA levels with a mean ratio (RT/LT)...
Periperal Plasma Renin Activity in Children with Normotensive Reflux Nephropathy.
Chong Guk Lee, Kwang Mann Ko
Clin Exp Pediatr. 1988;31(6):731-737.   Published online June 30, 1988
Peripheral renin activity was measured in 11 children with normotensive reflux nephropathy and 20 normal children to disclose the abnormality of the renin-angiotensin system in the patient group. 9 children among the patient group were allocated to single-dose captopril test for the assessment of the response to the test in patients with normotensive reflux nephropathy. 1. Contrary to the significant negative correlation between PRA and...
Plasma Renin Acivity in Children with Acute Glomerulonephritis and Nephrotic Syndrome.
Oh Kyun Kwon, Young Hun Chung
Clin Exp Pediatr. 1987;30(11):1213-1220.   Published online November 30, 1987
This is a study on plasma renin acitivity (PRA) which was obtanined from the patients with acute glomerulonephritis or nephrotic syndrome and normotensive control group admitted in Chungnam National University Hospital from Oct. 1985 to Aug. 1986 to confirm any differences of PRA between groups and to establish their influencing factors. The results were as follows; 1) PRA of noimal children in preschool age (3.49 ±0.98...
A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood.
Yeong Ho Ra, Sung Ho Cha, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(7):759-768.   Published online July 31, 1987
Clinical features of 96 cases (46 Mycoplasmal pneumonia: Group I, 50 Non-Mycoplasmal pneumo- nia: Group II) above 2 years of age were studied prospectively from December, 1985 to June, 1986 who were admitted to the Dept, of Pediatrics, Kyung Hee University Hospital. The summary of the study is as follows: 1) Among the total 96 cases with pneumonia above 2 years of age, the frequency...
Diagnosis and Treatment of Diabetes Insipidus in Childhood.
Yong Hoom Park, Jin Sang Son, Jeong Ok Hah
Clin Exp Pediatr. 1987;30(7):749-758.   Published online July 31, 1987
In eight cases of diabetes insipidus who were diagnosed at the pediatric department of Yeungnam University Hospital from July 1985 till May 1986, the levels of plaana AVP were measured by radioimmunoassay and the effects of various treatment were studied. In central diabetes insipidus patients basal plasma AVP level was 2.92 ±2.55 pg/ml which was significantly lower than the level of control group, 8.25...
Clinical Observation on Pneumonia due to Mycoplasma Pneumoniae in Children.
Baik Lin Eun, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(6):651-657.   Published online June 30, 1987
The author determined mycoplasma antibody titer in 216 cases of pneumonia who were admitted to the pediatric ward of Korea Medical Center Guro Hospital from November, 1985 to September, 1986, and clinical investigation and statistical analysis were performed between mycoplasma anti- body positive group and negative group. The following results were obtained: 1) In 216 cases of children with pneumonia, incidence of mycoplasma antibody positive cases...
Studies on the Changes of Serum Osmolality Electrolytes, Digoxin-like Substance and Plasma Renin Activity Following Angiocardiography using Hypertonic Contrast Media.
Heon Seob Song, Hyeong Won Shin, Chan Uhung Joo, Dae Yeol Lee, Jin Gon Jun
Clin Exp Pediatr. 1987;30(4):398-405.   Published online April 30, 1987
Angiocardiography and cineangiocardiography have been employed with increasing frequency for the diagnosis of cardiovascular diseases. These commonplace technics of cardiovascular radiology depend upon the rapid injection of hypertonic contrast media into the heart or central circulation. In order to study the effects of concentrated radiopaque materials(Conray®, 1382 mOsm/L, 1-2 ml/ kg) on hemodynamic consequences, the changes of serum osmolality, sodium, potassium, chloride, digoxin-like substance and...
Cord Plasma Alpha-Fetoprotein Values and Neonatal Jaundice.
Mee Kyung Namgoong, Sei Hee Choi, Ae Sook Kim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1986;29(8):836-839.   Published online August 31, 1986
Alpha-fetoprotein(aFP) levels were studied in 20 neonatally hyperbilirubinemic children and 20 controls matched for gestational age. The mean aFP value of cord blood (119+58.2산g/ml) with hyperbilirubinemic children was significantly greater than that(79.6±40.8/zg/ml) for the control infants(P<0.001). At the age of 3 and 5 days the mean serum aFP in hyperbilirubinemic children were higher compared with the control group, the difference...
A Study on Plasma Antidiuretic Hormone and Serum Sodium Levels of Cord Blood in the Newborn Infants.
Choon Ho Park, Chang Soo Ra
Clin Exp Pediatr. 1986;29(7):748-757.   Published online July 31, 1986
The authors studied the plasma antidiuretic hormone levels of cord blood in 40 cases of newborn infants and also studied the serum sodium levels of cord blood in 40 cases of newborn infants. For the purpose of analysis, the study subjects were divided into four group; 1st group of 17 cases of vaginal delivery infants with fetal distress, 2nd group...
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